Kat5^tm1Hko
Targeted Allele Detail

Summary

• Symbol: Kat5^tm1Hko
• Name: K(lysine) acetyltransferase 5; targeted mutation 1, Haruhiko Koseki
• MGI ID: MGI:6153936
• Synonyms: Tip60^fl, Tip60^flox
• Gene: Kat5 Location: Chr19:5653042-5660265 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Kat5^tm1Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244731
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 10 and a FRT-flanked Neo cassette and second loxP site were inserted downstream of exon 11. (J:244731)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kat5 Mutation: 28 strains or lines available

References

• Original: J:244731 Dong Y, et al., EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice. Mol Cell Biol. 2017 Oct 01;37(19)
• All: 1 reference(s)