Rnf168^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf168^em1(IMPC)H
• Name: ring finger protein 168; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6153814
• Gene: Rnf168 Location: Chr16:32096277-32120252 bp, + strand Genetic Position: Chr16, 22.51 cM, cytoband B2
• Alliance: Rnf168^em1(IMPC)H page
• IMPC: Rnf168 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 4 guide sequences TGGTGGGTTTTTATGGCCCAGGG, GGTTTTTATGGCCCAGGGCCTGG, AAGCCAACTAAATTACCTAGAGG, CCTCCCTATTAAAAGTATTTGGT, which resulted in a Exon Deletion. (J:237616)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf168 Mutation: 73 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)