Bscl2^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bscl2^em1(IMPC)H
• Name: BSCL2 lipid droplet biogenesis associated, seipin; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6153776
• Gene: Bscl2 Location: Chr19:8814831-8826047 bp, + strand Genetic Position: Chr19, 5.76 cM
• Alliance: Bscl2^em1(IMPC)H page
• IMPC: Bscl2 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and guides with spacer sequences AAGCCAGGGAGAACCACCTC, CTCTTGCACAATCACTGCAG, GGCAGATCATCTTGTTATCC, and GTGACAAGCACAGTGAAGCC that targeted exon(s) ENSMUSE00001217152.2 ENSMUSE00001242889.2 ENSMUSE00001247469.2. This resulted in deletion(s) of 2222 bp (location: Chr19:8821822-8824043; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Bscl2 Mutation: 37 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)