Zmym4^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zmym4^{em1(IMPC)Wtsi}
• Name: zinc finger, MYM-type 4; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6153718
• Gene: Zmym4 Location: Chr4:126755732-126861928 bp, - strand Genetic Position: Chr4, 61.05 cM
• Alliance: Zmym4^{em1(IMPC)Wtsi} page
• IMPC: Zmym4 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Wellcome Sanger Institute using Cas9 and guides with spacer sequences CCACCCTCTTGGTATATTAA, CGTAATGCATGTACAGAAAC, and TGCATCTTTTAGCCGAATAG that targeted exon(s) ENSMUSE00001219094.2 ENSMUSE00001281422.2. This resulted in deletion(s) of 762 bp (location: Chr4:126804377-126805138; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zmym4 Mutation: 134 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 5 reference(s)