Tm6sf2^em4(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tm6sf2^em4(IMPC)H
• Name: transmembrane 6 superfamily member 2; endonuclease-mediated mutation 4, Harwell
• MGI ID: MGI:6152701
• Gene: Tm6sf2 Location: Chr8:70525574-70532716 bp, + strand Genetic Position: Chr8, 34.15 cM
• Alliance: Tm6sf2^em4(IMPC)H page
• IMPC: Tm6sf2 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 4 guide sequences CCAAGTAGAAAACCTAACCAAGA, CCAGTGGGAGCAATATGGATAAG, GGCCTGGAATACCATTAGACTGG, CCATTAACTGTGGAACTCGGAGG, which resulted in a Exon Deletion. (J:237616)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tm6sf2 Mutation: 37 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 1 reference(s)