Slc25a14^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc25a14^em1(IMPC)Mbp
• Name: solute carrier family 25 (mitochondrial carrier, brain), member 14; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6152642
• Gene: Slc25a14 Location: ChrX:47712333-47751171 bp, + strand Genetic Position: ChrX, 25.69 cM
• Alliance: Slc25a14^em1(IMPC)Mbp page
• IMPC: Slc25a14 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences GAGGTTCTAGTCATGATATA, GGCTGAAACGTCTTTGGGTG, GGGTTTGCAAAAAAGAAGCC, and GTCTAGTTGAATGTCAGAGA that targeted exon(s) ENSMUSE00001205200.2 ENSMUSE00001227326.2. This resulted in deletion(s) of 283 bp (location: ChrX:47717534-47717816; GRCm39), 398 bp (location: ChrX:47717132-47717529; GRCm39), and 710 bp (location: ChrX:47717847-47718556; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc25a14 Mutation: 10 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)