Pi15^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pi15^em1(IMPC)Mbp
• Name: peptidase inhibitor 15; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6152615
• Gene: Pi15 Location: Chr1:17672125-17701163 bp, + strand Genetic Position: Chr1, 5.32 cM, cytoband A4
• Alliance: Pi15^em1(IMPC)Mbp page
• IMPC: Pi15 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences AGGGATATCAGTTTTGGGGA, GACATCTAATTGTAACATGG, GGTGTGTGGGTTTGGAAAGC, and GTATGGTCAATGGCAAATAC that targeted exon(s) ENSMUSE00000552632.2. This resulted in deletion(s) of 8 bp (location: Chr1:17690996-17691003; GRCm39), 1175 bp (location: Chr1:17689779-17690953; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pi15 Mutation: 18 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)