Prdm1^tm1.1Sait
Targeted Allele Detail

Summary

• Symbol: Prdm1^tm1.1Sait
• Name: PR domain containing 1, with ZNF domain; targeted mutation 1.1, Mitinori Saitou
• MGI ID: MGI:6152369
• Synonyms: EGFP-Blimp1 KI
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^tm1.1Sait page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260589
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An EGFP cDNA and a linker sequene were inserted into the first ATG of the gene. A loxP-flanked neomycin selection cassette was removed by cre-mediated recombination. (J:260589)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 69 strains or lines available

References

• Original: J:260589 Kurimoto K, et al., Quantitative Dynamics of Chromatin Remodeling during Germ Cell Specification from Mouse Embryonic Stem Cells. Cell Stem Cell. 2015 May 7;16(5):517-32
• All: 3 reference(s)