Reln^tm1Her
Targeted Allele Detail

Summary

• Symbol: Reln^tm1Her
• Name: reelin; targeted mutation 1, Joachim Herz
• MGI ID: MGI:6151449
• Synonyms: Reln^fl
• Gene: Reln Location: Chr5:22089452-22549700 bp, - strand Genetic Position: Chr5, 9.98 cM, cytoband A3-B1
• Alliance: Reln^tm1Her page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241635
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The first exon of the Reln gene was flanked with loxP sites. An frt-flanked neomycin selection cassette was inserted 3' to exon 1. (J:241635)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Reln Mutation: 209 strains or lines available

References

• Original: J:241635 Lane-Donovan C, et al., Reelin protects against amyloid beta toxicity in vivo. Sci Signal. 2015 Jul 07;8(384):ra67
• All: 7 reference(s)