Krt25^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Krt25^em1(IMPC)J
• Name: keratin 25; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6151423
• Gene: Krt25 Location: Chr11:99206342-99213777 bp, - strand Genetic Position: Chr11, 62.92 cM
• Alliance: Krt25^em1(IMPC)J page
• IMPC: Krt25 gene page

Mutation origin

• Strain of Origin: Not Specified
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences AAGTTCAGATTCTCTTGGTT, AGAGAGGCCAGCCTTAGCCG, GCATGCTACATGATTACTAG, and GTGAGCGAAAAGAATCCATG that targeted exon(s) ENSMUSE00000972994.2. This resulted in deletion(s) of 2 bp (location: Chr11:99213239-99213240; GRCm39), 3 bp (location: Chr11:99213207-99213209; GRCm39), and 357 bp (location: Chr11:99212670-99213026; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Krt25 Mutation: 28 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)