Hprt1^{tm10(Dct-tTA)Geno}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm10(Dct-tTA)Geno}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 10, Genoway
• MGI ID: MGI:6150915
• Synonyms: Hprt^{tm1(Dct-tTA)Geno}
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm10(Dct-tTA)Geno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259691
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: The expression vector Dct-tTA-SV40p(A) was inserted into the Hprt locus on the X chromosome. The tTA activator is expressed under the control of the mouse Dct promoter. (J:259691)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1280 strains or lines available

References

• Original: J:259691 Joshi SS, et al., Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors. Gene Expr Patterns. 2018 Jan;27:76-84
• All: 2 reference(s)