Gt(ROSA)26Sor^{tm1(Fgfr2_iIIIc)Pauw}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Fgfr2_iIIIc)Pauw}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Erwin Pauws
• MGI ID: MGI:6150825
• Synonyms: Fgfr2cV5, Gt(ROSA)26Sor^{tm1(Fgfr2IIIc)Pauw}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Fgfr2_iIIIc)Pauw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261451
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Modified isoform(s))
• Mutation: Insertion
• Mutation details: The Fgfr2-IIIc coding sequence was cloned into a vector containing a floxed cassette with a PGK-Neo selection marker and a tpA transcriptional stop sequence. By homologous recombination, this construct was inserted into the locus. Upon Cre-mediated excision of the selection cassette/stop sequence, the IIIc isoform is transcribed under control of the Gt(ROSA)26Sor promoter. (J:261451)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 957 strains or lines available

References

• Original: J:261451 Pauws E, Fgfr2_iIIIc knock-in. MGI Direct Data Submission. 2018
• All: 2 reference(s)