Pxdn^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Pxdn^tm1Itl
• Name: peroxidasin; targeted mutation 1, InGenious Targeting Laboratory
• MGI ID: MGI:6150656
• Gene: Pxdn Location: Chr12:29987607-30067657 bp, + strand Genetic Position: Chr12, 13.0 cM
• Alliance: Pxdn^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:255314
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Knockout mice were generated using the knock-out first targeting vector created by the Trans-NIH Knockout Mouse Project (KOMP) and obtained from the KOMP Repository (Project ID CSD 80013). (J:255314)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pxdn Mutation: 70 strains or lines available

References

• Original: J:255314 Bhave G, et al., The sulfilimine cross-link of collagen IV contributes to kidney tubular basement membrane stiffness. Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F596-F602
• All: 4 reference(s)