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Rbl2tm1.1Gfk
Targeted Allele Detail
Summary
Symbol: Rbl2tm1.1Gfk
Name: RB transcriptional corepressor like 2; targeted mutation 1.1, Graham F Kay
MGI ID: MGI:6149998
Synonyms: p130F2
Gene: Rbl2  Location: Chr8:91796685-91850472 bp, + strand  Genetic Position: Chr8, 44.25 cM
Alliance: Rbl2tm1.1Gfk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243383
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by unidirectional loxP sites and a FRT-flanked PGK-neomycin selection cassette. Flp-mediated recombination removed the selection cassette. (J:243383)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbl2 Mutation:  52 strains or lines available
References
Original:  J:243383 Tonks ID, et al., Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation. Oncogene. 2017 Jun 29;36(26):3789-3795
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory