Rbl2tm1.1Gfk
Targeted Allele Detail
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Symbol: |
Rbl2tm1.1Gfk |
Name: |
RB transcriptional corepressor like 2; targeted mutation 1.1, Graham F Kay |
MGI ID: |
MGI:6149998 |
Synonyms: |
p130F2 |
Gene: |
Rbl2 Location: Chr8:91796685-91850472 bp, + strand Genetic Position: Chr8, 44.25 cM
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Alliance: |
Rbl2tm1.1Gfk page
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Germline Transmission: |
Earliest citation of germline transmission:
J:243383
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exon 2 was flanked by unidirectional loxP sites and a FRT-flanked PGK-neomycin selection cassette. Flp-mediated recombination removed the selection cassette.
(J:243383)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rbl2 Mutation: |
52 strains or lines available
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Original: |
J:243383 Tonks ID, et al., Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation. Oncogene. 2017 Jun 29;36(26):3789-3795 |
All: |
1 reference(s) |
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