Slamf1^tm2Cpt
Targeted Allele Detail

Summary

• Symbol: Slamf1^tm2Cpt
• Name: signaling lymphocytic activation molecule family member 1; targeted mutation 2, Cox Terhorst
• MGI ID: MGI:6149972
• Gene: Slamf1 Location: Chr1:171594700-171628752 bp, + strand Genetic Position: Chr1, 79.54 cM
• Alliance: Slamf1^tm2Cpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260068
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A loxP site and hygromycin resistance cassette replaced exons 2 and 3. (J:244675)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slamf1 Mutation: 30 strains or lines available

Notes

This allele was generated in ES cells carrying Slamf6^tm1Cpt.

References

• Original: J:260068 De Calisto J, et al., SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors. Front Immunol. 2014;5:186
• All: 2 reference(s)