Pcbp1^tm1.1Ccp
Targeted Allele Detail

Summary

• Symbol: Pcbp1^tm1.1Ccp
• Name: poly(rC) binding protein 1; targeted mutation 1.1, Caroline C Philpott
• MGI ID: MGI:6149969
• Synonyms: Pcbp1^fl
• Gene: Pcbp1 Location: Chr6:86501462-86503171 bp, - strand Genetic Position: Chr6, 37.72 cM, cytoband D1
• Alliance: Pcbp1^tm1.1Ccp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244696
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The coding sequence was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted upstream of the coding sequence. (J:244696)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcbp1 Mutation: 32 strains or lines available

Notes

C57BL/6-129S/SvEv hybrid embryonic stem cells

References

• Original: J:244696 Ryu MS, et al., PCBP1 and NCOA4 regulate erythroid iron storage and heme biosynthesis. J Clin Invest. 2017 May 01;127(5):1786-1797
• All: 5 reference(s)