Prkd1^tm1Adkg
Targeted Allele Detail

Summary

• Symbol: Prkd1^tm1Adkg
• Name: protein kinase D1; targeted mutation 1, Alexander Kleger
• MGI ID: MGI:6149959
• Synonyms: PKD1-(Tet-ON)
• Gene: Prkd1 Location: Chr12:50388014-50695881 bp, - strand Genetic Position: Chr12, 21.78 cM, cytoband C1
• Alliance: Prkd1^tm1Adkg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246270
• Parent Cell Line: 2A (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Inducible)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• A doxycycline-induced knock-in was generated. (J:246270)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkd1 Mutation: 58 strains or lines available

References

• Original: J:246270 Sroka R, et al., Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation. J Cell Sci. 2016 Jun 15;129(12):2416-29
• All: 1 reference(s)