Rbm24^{tm1.1(rtTA)Thbr}
Targeted Allele Detail

Summary

• Symbol: Rbm24^{tm1.1(rtTA)Thbr}
• Name: RNA binding motif protein 24; targeted mutation 1.1 Thomas Braun
• MGI ID: MGI:6149957
• Gene: Rbm24 Location: Chr13:46571910-46584571 bp, + strand Genetic Position: Chr13, 23.61 cM
• Alliance: Rbm24^{tm1.1(rtTA)Thbr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259125
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with an IRES-rtTA expression cassette followed by an frt-flanked neomycin resistance cassette. FLP-mediated recombination removed the neomycin selection cassette. (J:259125)

Expression

In Mice Carrying this Mutation:

31 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm24 Mutation: 14 strains or lines available

References

• Original: J:259125 Yang J, et al., RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99
• All: 1 reference(s)