Macrod1^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Macrod1^{tm1.1(KOMP)Vlcg}
• Name: mono-ADP ribosylhydrolase 1; targeted mutation 1.1, Velocigene
• MGI ID: MGI:6149953
• Synonyms: tm1d
• Gene: Macrod1 Location: Chr19:7034178-7175422 bp, + strand Genetic Position: Chr19, 5.17 cM
• Alliance: Macrod1^{tm1.1(KOMP)Vlcg} page
• IMPC: Macrod1 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259625
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: A Velocigene cassette ZEN-Ub1 replaced a gene fragment containing 9303bp between positions 7131384-7140686 of Chromosome 19 (Genome Build37). The Velocigene cassette was removed by Cre-mediatd recombination, (J:259625)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Macrod1 Mutation: 17 strains or lines available

References

• Original: J:259625 Agnew T, et al., MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria. Front Microbiol. 2018;9:20
• All: 2 reference(s)