Bid^tm1Aef
Targeted Allele Detail

Summary

• Symbol: Bid^tm1Aef
• Name: BH3 interacting domain death agonist; targeted mutation 1, Ariel E Feldstein
• MGI ID: MGI:6149952
• Synonyms: Bid^fl
• Gene: Bid Location: Chr6:120870080-120894074 bp, - strand Genetic Position: Chr6, 57.02 cM
• Alliance: Bid^tm1Aef page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259847
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 through 4 were floxed. An FRT-flanked neomycin resistance cassette is present. (J:259847)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bid Mutation: 46 strains or lines available

References

• Original: J:259847 Lazic M, et al., Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice. J Hepatol. 2014 Jul;61(1):107-15
• All: 2 reference(s)