Daam2^tm1Tpy
Targeted Allele Detail

Summary

• Symbol: Daam2^tm1Tpy
• Name: dishevelled associated activator of morphogenesis 2; targeted mutation 1, Terry Yamaguchi
• MGI ID: MGI:6149781
• Synonyms: Daam2^lacZ
• Gene: Daam2 Location: Chr17:49763050-49871371 bp, - strand Genetic Position: Chr17, 25.5 cM
• Alliance: Daam2^tm1Tpy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228507
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An IRES-lacZ cassette and a loxP site flanked PGK-neo cassette were inserted into a PstI site in exon 10, creatuing a reporter-knockout allele. (J:228507)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Daam2 Mutation: 49 strains or lines available

References

• Original: J:228507 Ajima R, et al., DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly. Dev Biol. 2015 Dec 1;408(1):126-39
• All: 2 reference(s)