Prdm13^em4Jejo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prdm13^em4Jejo
• Name: PR domain containing 13; endonuclease-mediated mutation 4, Jane Johnson
• MGI ID: MGI:6149767
• Synonyms: Prdm13^deltaZF
• Gene: Prdm13 Location: Chr4:21677480-21685963 bp, - strand Genetic Position: Chr4, 8.78 cM
• Alliance: Prdm13^em4Jejo page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable, Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted 454 bp within the fourth exon. The predicted protein product is truncated at amino acid 602 and lacks the three C-terminal zinc-fingers with the addition of 25 nonsense amino acids in the terminal portion of the protein. (J:258875)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm13 Mutation: 48 strains or lines available

References

• Original: J:258875 Mona B, et al., Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787
• All: 2 reference(s)