Padi4^tm1Koma
Targeted Allele Detail

Summary

• Symbol: Padi4^tm1Koma
• Name: peptidyl arginine deiminase, type IV; targeted mutation 1, Koichi Matsuda
• MGI ID: MGI:6149749
• Gene: Padi4 Location: Chr4:140473176-140501547 bp, - strand Genetic Position: Chr4, 72.34 cM, cytoband E1
• Alliance: Padi4^tm1Koma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260360
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and 2, including the transcription initiation site, are replaced by a mouse PGK-1 promoter and neomycin-resistance gene. (J:260360)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Padi4 Mutation: 46 strains or lines available

References

• Original: J:260360 Tanikawa C, et al., Regulation of histone modification and chromatin structure by the p53-PADI4 pathway. Nat Commun. 2012 Feb 14;3:676
• All: 5 reference(s)