Prkcd^tm1.1Gwd
Targeted Allele Detail

Summary

• Symbol: Prkcd^tm1.1Gwd
• Name: protein kinase C, delta; targeted mutation 1.1, Gerald W Dorn II
• MGI ID: MGI:6149731
• Synonyms: prkcd^f
• Gene: Prkcd Location: Chr14:30317311-30348167 bp, - strand Genetic Position: Chr14, 18.82 cM
• Alliance: Prkcd^tm1.1Gwd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259503
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 10 and 11 were flanked with loxP sites plus an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:259503)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcd Mutation: 52 strains or lines available

References

• Original: J:259503 Song M, et al., Combined cardiomyocyte PKCdelta and PKCepsilon gene deletion uncovers their central role in restraining developmental and reactive heart growth. Sci Signal. 2015 Apr 21;8(373):ra39
• All: 2 reference(s)