Tg(Gfap-Cyth1*Y382F)5Jya
Transgene Detail

Summary

• Symbol: Tg(Gfap-Cyth1*Y382F)5Jya
• Name: transgene insertion 5, Junji Yamauchi
• MGI ID: MGI:6149499
• Transgene: Tg(Gfap-Cyth1*Y382F)5Jya Location: unknown
• Alliance: Tg(Gfap-Cyth1*Y382F)5Jya page

Transgene origin

• Strain of Origin: C57BL/6JJms

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Gfap-Cyth1*Y382F)5Jya expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Cyth1

• Mutation details: The mouse glial fibrillary acidic protein promoter drives the expression of a FLAG-tagged phosphorylation mutant cytohesin-1 with a phenylalanine substitution for tyrosine at position 382 (Y382F) with a Moloney murine leukemia virus intron. This line contains approximately 120 gene copies per genome and levels of mutant protein are higher in this line than in line 1. (J:259473)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:259473 Yamauchi J, et al., Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. Sci Signal. 2012 Sep 25;5(243):ra69
• All: 1 reference(s)