Pou3f2^tm1.1Lmame
Targeted Allele Detail

Summary

• Symbol: Pou3f2^tm1.1Lmame
• Name: POU domain, class 3, transcription factor 2; targeted mutation 1.1, Shintaroh Ueda
• MGI ID: MGI:6149148
• Synonyms: deltaGQP, Pou3f2^{tm1.1(dGQP)Lmame}
• Gene: Pou3f2 Location: Chr4:22482780-22488366 bp, - strand Genetic Position: Chr4, 9.73 cM
• Alliance: Pou3f2^tm1.1Lmame page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259381
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Modified isoform(s))
• Mutation: Intragenic deletion
• Mutation details: The region of the mouse gene that encodes all of the three homopolymeric amino acid repeats was deleted. A loxP-flanked neomycin selection cassette was removed in vitro in ES cells prior to the production of mice. (J:259381)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou3f2 Mutation: 21 strains or lines available

References

• Original: J:259381 Nasu M, et al., Mammalian-specific sequences in pou3f2 contribute to maternal behavior. Genome Biol Evol. 2014 Apr 7;6(5):1145-56
• All: 4 reference(s)