Slc32a1tm2.1Yyan
Targeted Allele Detail
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Symbol: |
Slc32a1tm2.1Yyan |
Name: |
solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 2.1, Yuchio Yanagawa |
MGI ID: |
MGI:6148233 |
Synonyms: |
VGATflox |
Gene: |
Slc32a1 Location: Chr2:158452687-158457668 bp, + strand Genetic Position: Chr2, 78.72 cM, cytoband H1-3
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Alliance: |
Slc32a1tm2.1Yyan page
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Germline Transmission: |
Earliest citation of germline transmission:
J:241981
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. The neomycin selection cassette was removed via FLP-mediated recombination. This creates a conditional-ready allele with exons 2 and 3 floxed and without the neomycin selection cassette.
(J:241981)
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Original: |
J:241981 Kayakabe M, et al., Motor dysfunction in cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice. Front Cell Neurosci. 2013;7:286 |
All: |
3 reference(s) |
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