Gli2^{tm1(Gli2/GFP)Reit}
Targeted Allele Detail

Summary

• Symbol: Gli2^{tm1(Gli2/GFP)Reit}
• Name: GLI-Kruppel family member GLI2; targeted mutation 1, Jeremy Reiter
• MGI ID: MGI:6148033
• Synonyms: Gli2^Gli2-GFP
• Gene: Gli2 Location: Chr1:118761862-118981349 bp, - strand Genetic Position: Chr1, 52.17 cM, cytoband E2-E4
• Alliance: Gli2^{tm1(Gli2/GFP)Reit} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258486
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: In ES cells carrying Gli2 ^Gt(XG045)Byg the gene trap locus was modified between a lox71 site and a lox66 site to insert a Gl12 cDNA fused to GFP. (J:258486)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gli2 Mutation: 173 strains or lines available

References

• Original: J:258486 Santos N, et al., A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity. J Cell Sci. 2014 Apr 1;127(Pt 7):1500-10
• All: 2 reference(s)