Il9^em1Tshu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il9^em1Tshu
• Name: interleukin 9; endonuclease-mediated mutation 1, Hai Qi
• MGI ID: MGI:6147867
• Gene: Il9 Location: Chr13:56627090-56630059 bp, - strand Genetic Position: Chr13, 30.06 cM
• Alliance: Il9^em1Tshu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 induced a deletion from position 70 to 1734 including part of exon 1 and all of exons 2-4. (J:258171)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il9 Mutation: 23 strains or lines available

References

• Original: J:258171 Wang Y, et al., Germinal-center development of memory B cells driven by IL-9 from follicular helper T cells. Nat Immunol. 2017 Aug;18(8):921-930
• All: 3 reference(s)