Pin1^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pin1^em1Gpt
• Name: peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6147616
• Synonyms: Pin1^em1Cflox, Pin1^em1Nju, Pin1^flox
• Gene: Pin1 Location: Chr9:20563335-20575008 bp, + strand Genetic Position: Chr9, 7.6 cM
• Alliance: Pin1^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3 were floxed. (J:257506)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pin1 Mutation: 20 strains or lines available

References

• Original: J:257506 Liang ES, et al., Peptidyl-prolyl isomerase Pin1 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in ApoE(-/-) mice. J Mol Cell Cardiol. 2018 Jan;114:334-344
• All: 1 reference(s)