Trim62^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Trim62^tm1Tac
• Name: tripartite motif-containing 62; targeted mutation 1, Taconic
• MGI ID: MGI:6147603
• Gene: Trim62 Location: Chr4:128777837-128805119 bp, + strand Genetic Position: Chr4, 62.38 cM
• Alliance: Trim62^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233910
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A selection cassette was inserted at the junction of the first exon and first intron, resulting in deletion of a portion of the exon 1 coding region and intron 1. (J:233910)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim62 Mutation: 21 strains or lines available

References

• Original: J:233910 Cao Z, et al., Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity. 2015 Oct 20;43(4):715-26
• All: 1 reference(s)