Olig2^tm1.1Qrlu
Targeted Allele Detail

Summary

• Symbol: Olig2^tm1.1Qrlu
• Name: oligodendrocyte transcription factor 2; targeted mutation 1.1, Q Richard Lu
• MGI ID: MGI:6144430
• Synonyms: Olig2^-
• Gene: Olig2 Location: Chr16:91022345-91025565 bp, + strand Genetic Position: Chr16, 52.6 cM
• Alliance: Olig2^tm1.1Qrlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258147
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The coding region was deleted following Cre-mediated recombination of flanking loxP sites. (J:258147)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olig2 Mutation: 47 strains or lines available

References

• Original: J:258147 Zuo H, et al., Age-Dependent Decline in Fate Switch from NG2 Cells to Astrocytes After Olig2 Deletion. J Neurosci. 2018 Feb 28;38(9):2359-2371
• All: 1 reference(s)