Tg(Myh6-Hsd11b2)326Pfzr
Transgene Detail

Summary

• Symbol: Tg(Myh6-Hsd11b2)326Pfzr
• Name: transgene insertion 326, Jeffrey Stock
• MGI ID: MGI:6144244
• Synonyms: Line 326
• Transgene: Tg(Myh6-Hsd11b2)326Pfzr Location: unknown
• Alliance: Tg(Myh6-Hsd11b2)326Pfzr page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Hsd11b2)326Pfzr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hsd11b2 (MGI:104720)

• Mutation details: The transgenic construct contains a 5.4-kb murine Myh6 promoter directing expression of the mouse hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2) cDNA, followed by human growth hormone and polyadenylation cassette. Founder line 326 has 29 copies of the transgene. (J:258076)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:258076 Qin W, et al., Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure. Circ Res. 2003 Jul 11;93(1):69-76
• All: 1 reference(s)