Mir128-2^tm1.1Ygw
Targeted Allele Detail

Summary

• Symbol: Mir128-2^tm1.1Ygw
• Name: microRNA 128-2; targeted mutation 1.1, Yigang Wang
• MGI ID: MGI:6144043
• Synonyms: miR-128^fl
• Gene: Mir128-2 Location: Chr9:111947704-111947779 bp, - strand Genetic Position: Chr9, 62.46 cM
• Alliance: Mir128-2^tm1.1Ygw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:257896
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A 1.7 kb fragment spanning the gene was flanked by loxP sites. A FRT-flanked neomycin cassette was inserted upstream of the second loxP site. Flp-mediated recombination removed the neomycin cassette. (J:257896)

Expression

In Mice Carrying this Mutation:

38 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir128-2 Mutation: 0 strains or lines available

References

• Original: J:257896 Huang W, et al., Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nat Commun. 2018 Feb 16;9(1):700
• All: 1 reference(s)