Gbp5^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gbp5^{em1(IMPC)Wtsi}
• Name: guanylate binding protein 5; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6140192
• Gene: Gbp5 Location: Chr3:142202695-142228105 bp, + strand Genetic Position: Chr3, 66.69 cM
• Alliance: Gbp5^{em1(IMPC)Wtsi} page
• IMPC: Gbp5 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Wellcome Sanger Institute using Cas9 and guides with spacer sequences ACAATATTCAAATGGCCCCG, AGTGAACTCGTGTAGACTCC, ATAGACATCAGGGTCACAGA, and GAGATGACAGTCACTTATGT that targeted exon(s) ENSMUSE00001086526.2 ENSMUSE00001743655.1. This resulted in deletion(s) of 527 bp (location: Chr3:142211020-142211546; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gbp5 Mutation: 40 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)