Cacna1i^tm1Hssh
Targeted Allele Detail

Summary

• Symbol: Cacna1i^tm1Hssh
• Name: calcium channel, voltage-dependent, alpha 1I subunit; targeted mutation 1, Hee-Sup Shin
• MGI ID: MGI:6140088
• Synonyms: CaV3.3^-
• Gene: Cacna1i Location: Chr15:80171439-80282480 bp, + strand Genetic Position: Chr15, 37.85 cM, cytoband E2
• Alliance: Cacna1i^tm1Hssh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213700
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A genomic region encompassing exons 3-4 was replaced with a neomycin selection cassette. (J:213700)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacna1i Mutation: 75 strains or lines available

References

• Original: J:213700 Lee SE, et al., Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11828-33
• All: 1 reference(s)