Tg(Aldh1l1-cre/ERT2)02Kan
Transgene Detail
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Symbol: |
Tg(Aldh1l1-cre/ERT2)02Kan |
Name: |
transgene insertion 02, Klaus-Armin Nave |
MGI ID: |
MGI:6121471 |
Synonyms: |
Aldh1l1-CreERT2 |
Transgene: |
Tg(Aldh1l1-cre/ERT2)02Kan Location: unknown
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Alliance: |
Tg(Aldh1l1-cre/ERT2)02Kan page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Aldh1l1-cre/ERT2)02Kan expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The transgene was generated by inserting a cre/ERT2 cassette into intron 1/ exon 2 of the mouse Aldh1l1 in a murine BAC (BAC RP23-7M9) by homologous recombination in bacteria. Pronucleus injection gave rise to 5 transgenic founder mice. Three out of five founder mice that were crossed with reporter mice showed expression in the brain. Only one line (line 02) showed robust expression in forebrain astrocytic cells and minimal expression in other cell types of the brain and was used for further analyses.
(J:247456)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Aldh1l1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:247456 Winchenbach J, et al., Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice. F1000Res. 2016;5:2934 |
All: |
8 reference(s) |
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