Wwtr1^tm1.1Picc
Targeted Allele Detail

Summary

• Symbol: Wwtr1^tm1.1Picc
• Name: WW domain containing transcription regulator 1; targeted mutation 1.1 Stefano Piccolo
• MGI ID: MGI:6120901
• Synonyms: Taz^flox
• Gene: Wwtr1 Location: Chr3:57363070-57483331 bp, - strand Genetic Position: Chr3, 27.74 cM
• Alliance: Wwtr1^tm1.1Picc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214515
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites flank exons 1 and 2. An adjacent frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:214515)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wwtr1 Mutation: 23 strains or lines available

References

• Original: J:214515 Azzolin L, et al., YAP/TAZ incorporation in the beta-catenin destruction complex orchestrates the Wnt response. Cell. 2014 Jul 3;158(1):157-70
• All: 17 reference(s)