Icam2^m1Dvs
Spontaneous Allele Detail

Summary

• Symbol: Icam2^m1Dvs
• Name: intercellular adhesion molecule 2; mutation 1, David V Serreze
• MGI ID: MGI:6120486
• Gene: Icam2 Location: Chr11:106268482-106278901 bp, - strand Genetic Position: Chr11, 69.09 cM
• Alliance: Icam2^m1Dvs page

Mutation origin

• Strain of Origin: NOD/ShiLtDvs

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exome sequencing shows this spontaneous intragenic deletion removes all exons except the last one (ENSMUSE00000374954) and this mutation is believed to have arisen in the NOD/ShiLtDvs inbred substrain in approximately the year 2000. (J:257336)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Icam2 Mutation: 13 strains or lines available

References

• Original: J:257336 Simecek P, et al., Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice. G3 (Bethesda). 2015 Mar 3;5(5):771-5
• All: 1 reference(s)