Krit1^tm2Dmar
Targeted Allele Detail

Summary

• Symbol: Krit1^tm2Dmar
• Name: KRIT1, ankyrin repeat containing; targeted mutation 2, Douglas Marchuk
• MGI ID: MGI:6119715
• Synonyms: Krit1^fl
• Gene: Krit1 Location: Chr5:3853156-3894515 bp, + strand Genetic Position: Chr5, 2.26 cM
• Alliance: Krit1^tm2Dmar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:249865
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 5 was flanked by loxP sites. (J:249865)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krit1 Mutation: 35 strains or lines available

References

• Original: J:249865 Lopez-Ramirez MA, et al., Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 6;214(11):3331-3346
• All: 5 reference(s)