Zc3h12a^tm1Pako
Targeted Allele Detail

Summary

• Symbol: Zc3h12a^tm1Pako
• Name: zinc finger CCCH type containing 12A; targeted mutation 1, Pappachan Kolattukudy
• MGI ID: MGI:6118050
• Synonyms: MCPIP-LoxP
• Gene: Zc3h12a Location: Chr4:125012216-125021633 bp, - strand Genetic Position: Chr4, 58.1 cM
• Alliance: Zc3h12a^tm1Pako page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244458
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted in intron 2 and a loxP flanked PGK-promoter driven neomycin resistance gene were inserted in intron 4 so that exons 3 to 4 are floxed. (J:244458)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zc3h12a Mutation: 34 strains or lines available

References

• Original: J:244458 Kapoor N, et al., Transcription factors STAT6 and KLF4 implement macrophage polarization via the dual catalytic powers of MCPIP. J Immunol. 2015 Jun 15;194(12):6011-23
• All: 2 reference(s)