Rr47^em1Phg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr47^em1Phg
• Name: regulatory region 47; endonuclease-mediated mutation 1, Phillip Grote
• MGI ID: MGI:6117838
• Synonyms: Lmo2-70^deltaTBS
• Gene: Rr47 Location: Chr2:103731755-103732196 bp Genetic Position: Chr2, Syntenic
• Alliance: Rr47^em1Phg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:257034
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region, Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 400 bp region in the -70 kb enhancer of Lmo2 was removed. (J:257034)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr47 Mutation: 0 strains or lines available

References

• Original: J:257034 Beisaw A, et al., BRACHYURY directs histone acetylation to target loci during mesoderm development. EMBO Rep. 2018 Jan;19(1):118-134
• All: 1 reference(s)