Mir125a^em1Seco
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir125a^em1Seco
• Name: microRNA 125a; endonuclease-mediated mutation 1, Susan E Cole
• MGI ID: MGI:6117775
• Synonyms: mir-125a-5p^delta11
• Gene: Mir125a Location: Chr17:18051074-18051141 bp, + strand Genetic Position: Chr17, 10.5 cM
• Alliance: Mir125a^em1Seco page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• An 11 bp deletion was created just 5' of the mature miRNA sequence. (J:243775)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir125a Mutation: 4 strains or lines available

References

• Original: J:243775 Wahi K, et al., Putative binding sites for mir-125 family miRNAs in the mouse Lfng 3'UTR affect transcript expression in the segmentation clock, but mir-125a-5p is dispensable for normal somitogenesis. Dev Dyn. 2017 Oct;246(10):740-748
• All: 1 reference(s)