Tbx1^M1Wxi
Chemically induced Allele Detail

Summary

• Symbol: Tbx1^M1Wxi
• Name: T-box 1; mutation 1, Wei Xiong
• MGI ID: MGI:6117754
• Synonyms: ENU706
• Gene: Tbx1 Location: Chr16:18399729-18409412 bp, - strand Genetic Position: Chr16, Syntenic
• Alliance: Tbx1^M1Wxi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transversion causing a tryptophan to arginine change at the 118 amino acid (W118R) in the T-box region of the protein. (J:244462)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx1 Mutation: 36 strains or lines available

References

• Original: J:244462 Chen J, et al., Identification of a Novel ENU-Induced Mutation in Mouse Tbx1 Linked to Human DiGeorge Syndrome. Neural Plast. 2016;2016:5836143
• All: 1 reference(s)