Spns2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Spns2^tm1Lex
• Name: SPNS lysolipid transporter 2, sphingosine-1-phosphate; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:6117328
• Gene: Spns2 Location: Chr11:72342464-72380730 bp, - strand Genetic Position: Chr11, 44.31 cM
• Alliance: Spns2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237609
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exon 3 was replaced with a beta-geo/puromycin selection cassette via homologous recombination. (J:237609)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spns2 Mutation: 36 strains or lines available

References

• Original: J:237609 Donoviel MS, et al., Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases. FASEB J. 2015 Dec;29(12):5018-28
• All: 1 reference(s)