Vps33b^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Vps33b^tm1Smoc
• Name: vacuolar protein sorting 33B; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6117087
• Synonyms: Vps33b^fl, Vps33b^tm1Srcmo
• Gene: Vps33b Location: Chr7:79919369-79941323 bp, + strand Genetic Position: Chr7, 45.59 cM
• Alliance: Vps33b^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239696
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3 were flanked by loxP sites. (J:239696)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vps33b Mutation: 31 strains or lines available

References

• Original: J:239696 Gu H, et al., Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. J Clin Invest. 2016 Dec 01;126(12):4537-4553
• All: 2 reference(s)