Trpm6^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Trpm6^tm1.1Arte
• Name: transient receptor potential cation channel, subfamily M, member 6; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6116847
• Synonyms: Trpm6^fl
• Gene: Trpm6 Location: Chr19:18727347-18869875 bp, + strand Genetic Position: Chr19, 13.21 cM
• Alliance: Trpm6^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239386
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 17 was flanked by loxP sites. In addition a FRT flanked neomycin resistance cassette was inserted which was removed via Flp-mediated recombination. (J:239386)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpm6 Mutation: 111 strains or lines available

References

• Original: J:239386 Chubanov V, et al., Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. Elife. 2016 Dec 19;5:e20914
• All: 1 reference(s)