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Pgrtm1Ics
Targeted Allele Detail
Summary
Symbol: Pgrtm1Ics
Name: progesterone receptor; targeted mutation 1, Mouse Clinical Institute
MGI ID: MGI:6116837
Synonyms: PRloxP
Gene: Pgr  Location: Chr9:8899834-8968612 bp, + strand  Genetic Position: Chr9, 2.46 cM
Alliance: Pgrtm1Ics page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:254871
Parent Cell Line:  P1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exon 2 was flanked by loxP sites. (J:254871)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pgr Mutation:  76 strains or lines available
References
Original:  J:254871 Zhu X, et al., A Role of Endogenous Progesterone in Stroke Cerebroprotection Revealed by the Neural-Specific Deletion of Its Intracellular Receptors. J Neurosci. 2017 Nov 8;37(45):10998-11020
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory