Tg(CAG-lacZ,Mstn,-EGFP)1Thbr
Transgene Detail

Summary

• Symbol: Tg(CAG-lacZ,Mstn,-EGFP)1Thbr
• Name: transgene insertion 1, Thomas Braun
• MGI ID: MGI:6116686
• Synonyms: CAGG-Mstn, Mstn-IRES2-EGFP
• Transgene: Tg(CAG-lacZ,Mstn,-EGFP)1Thbr Location: unknown
• Alliance: Tg(CAG-lacZ,Mstn,-EGFP)1Thbr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-lacZ,Mstn,-EGFP)1Thbr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mstn (MGI:95691)

• Mutation details: This transgene contains a loxP-flanked lacZ/neo gene fusion under the control of a CAG promoter, followed by a Myostatin-IRES-EGFP cassette. Beta-geo is expressed. Upon Cre-mediated recombination, myostatin and EGFP are expressed. (J:247083)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:247083 Biesemann N, et al., Myostatin regulates energy homeostasis in the heart and prevents heart failure. Circ Res. 2014 Jul 07;115(2):296-310
• All: 2 reference(s)