Hspd1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Hspd1^tm1.1Arte
• Name: heat shock protein 1 (chaperonin); targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6116674
• Synonyms: Hsp60^flox
• Gene: Hspd1 Location: Chr1:55116994-55127402 bp, - strand Genetic Position: Chr1, 28.01 cM
• Alliance: Hspd1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:242638
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 4 to 8 (chaperone ATPase domain) were flanked by loxP sites. A F3-site flanked puromycin resistance cassette was inserted in intron 3 which was removed via Flp-mediated recombination. (J:242638)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hspd1 Mutation: 48 strains or lines available

References

• Original: J:242638 Berger E, et al., Mitochondrial function controls intestinal epithelial stemness and proliferation. Nat Commun. 2016 Oct 27;7:13171
• All: 2 reference(s)